Cell Cycle Regulation in Hematopoietic Stem/Progenitor Cells
نویسندگان
چکیده
منابع مشابه
Cell cycle regulation in hematopoietic stem cells
This review focuses on the cell cycle of hematopoietic stem cell and its regulatory mechanisms. Owing to recent advances in cell culture techniques and analyzing tools, hematopoietic stem cells can be purified from bone marrow, peripheral blood, and umbilical cord blood by using specific surface markers such as Sca-1 (murine) and CD34 (human). Stem cell compartment includes primitive stem cells...
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Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system and in the regulation of HSC fate, little is currently known about the specific mechanisms that are involved. We identified transcriptome changes induced by hypoxia, constitutively active HIF1(P402/564) and HIF2(P405/531) in human cord blood CD34+ cells. Thus, we were able to identify common hypox...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2004
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.3.3.710